Components of nucleic acids Nucleotide bases Nucleic acids are the acidic component of nuclei, first identified by Meischer in the late 19th century. Know the three chemical components of a nucleotide: a monosaccharide residue (either ribose or deoxyribose), at least one phosphate … It codes genetic information for the transmission of inherited traits. You can change your ad preferences anytime. The first isolation of what we now refer to as DNA was accomplished by Johann Friedrich Miescher circa 1870. Illustrate structure of nucleotides. Nucleic Acids 1. You can change your ad preferences anytime. Now customize the name of a clipboard to store your clips. Title: nucleic acid 1 NUCLEIC ACID 2 NUCLEIC ACID. M.D 2. Looks like you’ve clipped this slide to already. Now customize the name of a clipboard to store your clips. Genomic DNA is found in the nucleus of all living cells with … Such stored information is known to control the inherited characteristics … • These are of two types: • Deoxyribonucleic acid (DNA) • Ribonucleic acid … See our Privacy Policy and User Agreement for details. Nucleic acids play a significant role in this process. A and G are categorized as purines, and C, T, and U … Nucleotides are held together by peptide bonds. Professor and Head The functions of nucleic acids have to do with the storage and expression of genetic information. A single nucleotide is made up of three components: a nitrogen-containing base, a five-carbon sugar (pentose), and at least one phosphate group With all three joined, a nucleotide is also termed a “nucleoside phosphate”. • Huge organic molecules that contains C, H, O, N, & P. • Nucleic acid is a polymer of NUCLEOTIDE held by 3’ and 5’ phosphate bridges. Although nucleic acid chemistry appears to be a mature part of organic and bioorganic chemistry, the many questions that are still being raised by research in biology and chemical biology give sufficient motivation to continue to synthesize new nucleic acid probes and thereby further develop nucleic acid chemistry… If you continue browsing the site, you agree to the use of cookies on this website. (DNA and RNA). Nucleic Acid • First discovered in the nuclei of cells. Metabolism of Purine & Pyrimidine nucleotide, Purine pyrimidine metabolism and disorder, Biomolecular ligand-receptor-binding-studies-theory, Central University of Gujarat, Gandhinagar, Nucleic acid chemistry for 1st year medical 5 04-2016, No public clipboards found for this slide. Introduction:
Frederic Miesher in 1869, isolated an acidic compound from the nuclear material of SALMON sperms, and named it as NUCLIEN which is now called NUCLEIC ACID.
Jones in 1920 proved the fact there are two types of nucleic acids, i.e., Deoxyribo nucleic acid (DNA) and Ribonucleic acid … Viral infections can pose a mild risk to our health, like the common cold, or a threat to our lives, like an HIV infection. Each nucleotide has three components: 1. Indian medical graduate - goals, roles and competencies, Acid base balance - Regulation of pH of body fluids, No public clipboards found for this slide. If you continue browsing the site, you agree to the use of cookies on this website. Separation of the nucleic acids from other cellular components • Purification of nucleic acids . If you continue browsing the site, you agree to the use of cookies on this website. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. He found it behaved as an acid, so the material was renamed nucleic acid. A free online book on the chemistry and biology of nucleic acids, written by Prof. Tom Brown and Dr Tom Brown (Jnr). R.C. Objectives By the end of lecture the student should: Define nucleic acids. Three of the nitrogen bases are the same. Nucleic acid is an important class of macromolecules found in all cells and viruses. Structure of Nucleic Acids. Five-carbon-ring sugar (deoxyribose or ribose) 2. Chapter 22. Gupta He reported finding a weakly acidic substance of unknown function in the nuclei of human white blood cells, and named this material \"nuclein\". Nucleoside, a structural subunit of nucleic acids, the heredity-controlling components of all living cells, consisting of a molecule of sugar linked to a nitrogen-containing organic ring compound.In the most … Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. See our User Agreement and Privacy Policy. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base.If the sugar is a compound ribose, the polymer is RNA (ribonucleic acid… The molecular structure of nucleic acid store this information in the coded form. BISSMILLAH AHRAHMAN AR-RAHEEM.
2. Jaipur, India Nucleic acid chemistry 1. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Nucleic acids … Viruses can be grouped … Each nucleic acid contains four of five possible nitrogen-containing bases: adenine (A), guanine (G), cytosine (C), thymine (T), and uracil (U). The structure of … Phosphate group 3. Definition Nucleic acid may be defined as the polymer of nucleotides connected by 3’-5’ phosphodiester bond 8. Department of Biochemistry Components Components are similar to its monomer (nucleotide): 1. We will now turn to the chemistry of nucleic acids. DNA Structure. Nucleic acids are biological macromolecules ; They are members of a family of biopolymers essential for life, and include DNA and RNA ; nucleic acids function in encoding, transmitting and expressing genetic information. List functions of nucleotides. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid … Elemental analysis of nucleic … Viruses are everywhere -- and abundant. Nitrogenous base + a pentose sugar + a phosphate group. NUCLEIC ACIDS :
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